HTLT Turk Builder Max

Take one capsule to assess tolerance. Take 1-3 capsules 30 minutes before exercise on training days. Take 1-2 capsules in the morning on non-training days. Do not exceed 3 capsules in one day. May affect sleep in some individuals when taken too close to bedtime, it is recommended not to take after 4pm.

Uzbek Ajuga Turkestanica Extract (std. for Turkesterone & 20HE)

Turkesterone and Ecdysteroids are structurally different from anabolic steroids and therefore work differently, ecdysteroids do not suppress natural sex hormone production and have not been shown to be toxic, they are found in tiny percentages in foods like spinach and quinoa.

Rhodiola Heterodonta

Rhodiola Heterodonta is a perennial herb harvested from the high altitudes of the wilderness in Uzbekistan and Central Asia. It is a distinct species from the commonly known Rhodiola Rosea, grows in a different region and contains a unique spectrum of bioactive ingredients.

According to Yousef et al. (2006) “R. heterodonta contained a newly detected phenylethanoid glycoside, heterodontoside, in addition to the known compounds tyrosol, viridoside, salidroside, and rhodiocyanoside A.”

Our Rhodiola Heterodonta extract contains a high concentration of bioactive compounds (salidroside, flavonoids, organic acids, triterpenoids amongst others). Rhodiola Heterodonta may feel more stimulating than generic Rhodiola preparations on the market, we stand by the potency of this extract.

Rhodiola Heterodonta is traditionally consumed as a stimulating agent during periods of exhaustive physical demand, Khojimatov et al (2023) states: “(it is) recommended as a herbal supplement in persons with an inclination to asthenia (especially in work requiring an increased mental load)”.

This ingredient may potentiate the effects of Ajuga Turkestanica and compliment it well as they both are indicated for improving athletic performance and reducing fatigue. By expert opinion and dose experimentation, it is supported that Rhodiola Heterodonta is synergistic with Ajuga Turkestanica Extract and thus emerged as a popular combo with athletes in Uzbekistan.

Capsorb (Sodium Caprate)

Sodium caprate, a medium chain fatty acid, is one of the most effective pharmaceutical-grade absorption enhancers amongst its class. It increases tight junction permeability in the intestinal epithelium, thereby allowing for greater absorption of drugs/supplements with poor oral bioavailability.*

Black Pepper Fruit Extract

Black pepper is used to enhance bioavailability in supplements.  There is no direct research that Black Pepper Extract directly helps the absorption of Ecdysterones, but it has been shown to increase absorption of vitamins and other nutrients.

Piperine is a component of black pepper extract which is an established bioenhancer of many different nutraceuticals, it works by enhancing intestinal absorption of many poorly absorbed compounds and slowing the rate at which certain compounds are broken down by the liver; leading to increased serum concentrations and a greater AUC (area under the curve, related to pharmacokinetics).* 

Labs backing label claims: Lab #1

For all batches, see Batch Report Repository

Ismailov, S.I., Maksutova, N.N. (2015).Clinical study of the effectiveness and tolerability of the biologically active food supplement "Ecditon" produced by "BIOTON" LLC (Uzbekistan), in patients with type 2 diabetes mellitus. Endocrinology of the Ministry of Health of the Republic of Uzbekistan. https://drive.google.com/file/d/1tK8cu6L7q7W-xcF10Hzu9P0PctTMdHSv/view?usp=drive_link

Sultanov, S.N., Mamatkasimov, A.M. (2014).Protocol for a clinical trial of a biologically
active food supplement «Ecdirefin», in the Republican Specialized Scientific and
Practical Medical Center for Obstetrics and Gynecology.
https://drive.google.com/file/d/1eayRiKrsgDngatmUmdQiZ9WaODfR2Xdp/view?usp=drive_link

Lawrence, M.M. (2012). Ajuga Turkestanica as a Countermeasure Against Sarcopenia and Dynapenia. Unpublished master’s thesis. Appalachian State University, Boone, NC.
https://core.ac.uk/download/pdf/149240702.pdf

Smetanin, B.Y. The Influence of Preparations of Plant Origin on Physical Work Capacity; The Russian Ministry of Public Health: Moscow, Russian, 1986. https://docs.google.com/document/d/1fZw3CM-U170X-TnDqNMIHALDIyD94jRs/edit?usp=sharing&ouid=115053821767806664957&rtpof=true&sd=true

Simakin, S.Y.; Panyushkin, V.V.; Portugalov, S.N.; Kostina, L.V.; Martisorov, E.G. Combined application of preparation Ecdysten and product Bodrost during training in cyclic sports. Sports Sci. Bull. 1988, 2, 29–31. https://drive.google.com/file/d/1u7eNTnyhastHa-MbaLaY8EhOGOtQg6iR/view?usp=sharing

Gadzhieva, R.M.; Portugalov, S.N.; Paniushkin, V.V.; Kondrat’eva, I.I. A comparative study of the anabolic action of Ecdysten, Leveton and Prime Plus, preparations of plant origin. Eksp Klin Farmakol. 1995, 58, 46–48. https://drive.google.com/file/d/1hDIG-nux1hybffQ9m807sKkYH97T0faV/view?usp=sharing

Azizov, A.P.; Seifulla, R.D.; Ankudinova, I.A.; Kondrat’eva, I.I.; Borisova, I.G. Effect of the antioxidants elton and leveton on the physical work capacity of athletes. Eksp Klin Farmakol. 1998, 61, 60–62. https://drive.google.com/file/d/1FNpuHY12g9IMzhMcvwn1ZQnoouhoH4bg/view?usp=sharing

Dustmukhamedova, D.K.H.; Kamilovz, A.T. The characteristic of energy metabolism disorders and its correction in children with celiac disease. Am. J. Med. Medic. Sci. 2020, 10, 780–783. https://drive.google.com/file/d/1R19U4LdPN8FL4sU7-fbEG25gmkjkYIZP/view?usp=sharing

Seidlova-Wuttke, D.; Wuttke, W. In a placebo-controlled study β-ecdysone (ECD) prevented the development of the metabolic syndrome. Planta Med. 2012, 78, CL37. https://drive.google.com/file/d/1J-dDgrC4cYziLaHCrT3qS9zyrMq7xPm1/view?usp=sharing


Emirova, L.R.; Rozhkova, E.A.; Paniushkin, V.V.; Mirzolan, R.S.; Seifulla, N.R. The effects of cytamines and their combinations with Ecdysten, Apilak, Vitamax and Essentiale on the work capacity of athletes. Eksp Klin Farmakol. 2004, 67, 66–68. https://drive.google.com/file/d/1Pgsq0rz5crfQM78ltvGJBzxsC8NY2edH/view?usp=sharing

Semenov, V. Trial of the Leuzea-containing preparation «Rus-Olympic» under extreme conditions. In Leuzea and Your Health; Antoshechkin, A., Ed.; Ceptima Publishing Inc.: Clearwater, FL, USA, 2000.

Safarova, D.D.; Tursunov, N.B. Aspects of sports medicine: The effect of Ekdisten. Sci. Sports Curr. Trends 2016, 12, 52–57. https://drive.google.com/file/d/1y6CcIQD7Gf1eaZ-ojGJ0tAuoYPEF4m1s/view?usp=sharing

Isenmann, E.; Ambrosio, G.; Joseph, J.F.; Mazzarino, M.; de la Torre, X.; Zimmer, P.; Kazlauskas, R.; Goebel, C.; Botrè, F.; Diel, P.; et al. Ecdysteroids as non-conventional anabolic agent: Performance enhancement by ecdysterone supplementation in humans. Arch. Toxicol. 2019, 93, 1807–1816 http:/doi.org/10.1007/s00204-019-02490-x

Lafont, R., Balducci, C., & Dinan, L. (2021). Ecdysteroids. Encyclopedia, 1(4), 1267–1302. https://doi.org/10.3390/encyclopedia1040096

Sarconeos—Biophytis—AdisInsight. (2022). https://adisinsight.springer.com/drugs/800045685

COVID-19: COVA clinical program. (n.d.). Biophytis. Retrieved July 2, 2022, from https://www.biophytis.com/en/pipeline/covid19-programme-clinique-cova/

Sarcopenia: SARA clinical program. (n.d.). Biophytis. Retrieved July 2, 2022, from https://www.biophytis.com/en/pipeline/plateforme-sarcob/

Sarconeos (BIO101). (n.d.). Biophytis. Retrieved July 2, 2022, from https://www.biophytis.com/en/our-science/sarcopenie/

Ecdysteroids as non-conventional anabolic agents: Pharmacodynamics, pharmacokinetics, and detection of ecdysterone. (2019). World Anti-Doping Agency. https://www.wada-ama.org/en/resources/funded-scientific-research/ecdysteroids-non-conventional-anabolic-agents-pharmacodynamics

Syrov, V. (2006). Comparative experimental investigation of the anabolic activity of phytoecdysteroids and steranabols. Pharmaceutical Chemistry Journal. https://doi.org/10.1007/BF02524596

Lafont, R., Serova, M., Didry-Barca, B., Raynal, S., Guibout, L., Dinan, L., Veillet, S., Latil, M., Dioh, W., & Dilda, P. J. (2021). 20-Hydroxyecdysone activates the protective arm of the RAAS via the MAS receptor. Journal of Molecular Endocrinology, 68(2), 77–87. https://doi.org/10.1530/JME-21-0033

Figure 1) Davranov, Kakhramon & Jabborova, Dilfuza. (2020). Phytochemical, pharmacological and biological properties of Ajuga turkestanica (Rgl.) Brig (Lamiaceae). Annals of Phytomedicine: An International Journal. 9. 10.21276/p.2020.9.1.6.

Twarog, C., Fattah, S., Heade, J., Maher, S., Fattal, E., & Brayden, D. J. (2019). Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C10). Pharmaceutics, 11(2), 78. https://doi.org/10.3390/pharmaceutics11020078

Khojimatov, O.K., Khujanov, A.N., Bussmann, R.W. (2023). Rhodiola heterodonta (Hook.f. & Thomson) Boriss., Rhodiola pamiroalaica Boriss. - CRASSULACEAE . In: Khojimatov, O.K., Gafforov, Y., Bussmann, R.W. (eds) Ethnobiology of Uzbekistan. Ethnobiology. Springer, Cham. https://doi.org/10.1007/978-3-031-23031-8_64

Mr, Z., Sn, G., Rr, M., Aa, M., Nl, V., Ug, G., Sm, M., & Tf, A. (2024). Characterization of Rhodiola heterodonta (Crassulaceae): Phytocomposition, Antioxidant and Antihyperglycemic Activities. Preventive nutrition and food science, 29(2), 135–145. https://doi.org/10.3746/pnf.2024.29.2.135

Yousef, G. G., Grace, M. H., Cheng, D. M., Belolipov, I. V., Raskin, I., & Lila, M. A. (2006). Comparative phytochemical characterization of three Rhodiola species. Phytochemistry, 67(21), 2380–2391. https://doi.org/10.1016/j.phytochem.2006.07.026